Search results: “MOK”

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Scientific Posters Detection of Endogenous Ligand Bias: A Case Study Using the Chemokine Receptor Family

The pattern of intracellular signaling downstream of GPCR activation is now known to be specific to the ligand-receptor pair as…

Scientific Posters PathHunter® β-Arrestin Assays: Determination of Pharmacology Differences Between Human and Ortholog GPCRs

DiscoveRx previously introduced a protein-protein interaction system using enzyme fragment complementation that provides a robust, HTS friendly format for monitoring…

Scientific Posters Phenotypic Characterization of CFTR Drugs, VX-770 and VX-809, in BioMAP® Human Primary Cell Systems Connects Target Biology to Disease Mechanisms

Cystic fibrosis (CF) patients have mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel that result in reduced…

Presentations [Cytokines Summit 2022] Enabling Cytokine Therapeutic Development with Qualified, Functional Cell-Based Assays

Gaurav Agrawal, Ph.D.Scientific Development Manager Discover how cell-based assays and translational services accelerate cytokine-based immunotherapeutic development from early discovery to…