CELL LINES AND PRIMARY CELLS

Engineered cell lines are essential for in vitro cell-based assays replicating biological systems' physiology. Cell lines are developed reflecting the target’s mechanism of action (MOA) with a drug interaction in a standard cell line background. Cell lines can be propagated repeatedly and kept in culture for extended periods of time. These cells provide the ability to deliver more physiologically relevant results in a cost-effective manner reproducibly.

Eurofins DiscoverX^® provides the most extensive collection of >1,000 fully qualified, functional cell lines that enable unique drug discovery and development solutions at every stage of your program. Cell lines covering all major drug target classes including GPCRs, cytokines, kinases, checkpoint inhibitors, ion channels, and nuclear proteins such as transcription factors, NHRs, and epigenetic proteins.

With over two decades of experience in generating stable cell lines, Eurofins DiscoverX provides cell lines with unsurpassed quality and industry-validated performance. These cell lines have been used to screen billions of data points to help bring many therapeutics to the market, with many more in the pipeline.

Use the appropriate application-specific detection kits with your cell line model for a complete functional cell-based assay to interrogate the MOA of your small molecule or biologic, measure and rank ligands' potencies, perform binding and functional screens, implement as a lot release assay, and much more.