Scientific Posters

Showing 25–36 of 71 results

Scientific Posters Ready-to-use potency assays for anti-VEGF drugs such as Bevacizumab

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

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Scientific Posters Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, & Ranibizumab

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

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Scientific Posters Simple, Reproducible & Robust Bioassays in Cryopreserved Ready-To-Assay Format

Cell-based bioassays often pose a hurdle during a rapidly moving biologics development program. High standards for assay accuracy, precision, reproducibility…

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Scientific Posters Single Donor KILR® CD16 Effector Cells to Drive Robust and Reproducible ADCC and T Cell Redirection

Class I therapeutic antibodies achieve their clinical efficacy not only by binding to their target antigen, but also through Fc…

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Scientific Posters Specifically Measure Target Cell Death in a Co-Culture with Immune Cells Through a Non-Radioactive, Dye-Free Cytotoxicity Assay

Following the recent regulatory approvals of a number of checkpoint inhibitor therapeutics, development of a wide array of immunomodulatory therapeutic…

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Scientific Posters SPRINTer Platform: Detection of Endogenous Protein Turnover and Target Engagement of Targeted Degraders

An assay platform that robustly and sensitively quantifies the kinetics of endogenous protein turnover and target engagement is crucial for…

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Scientific Posters The application of EFC technology to study forward trafficking of GPCRs

DiscoveRx has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…

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Scientific Posters Multi-Parameter GPCR Screening: An Essential Tool for Uncovering GPCR Mutant Phenotypes

The recent appreciation of functional selectivity/ligand bias in GPCR signaling has uncovered new opportunities for therapeutic discovery and continues to…

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Scientific Posters Novel Trafficking Assays For Pharmacochaperone Discovery Using Enzyme Fragment Complementation Applied To CFTR-ΔF508

DiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…

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Scientific Posters Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation

DiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…

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Scientific Posters New PathHunter Reporter Assays: Analysis of PD-1 Checkpoint Receptor and NFAT Signaling Pathways

Reporter genes are a well-established method used to develop cell-based assays for testing drugs that inhibit targets involved in specific…

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Scientific Posters New Cell-Based Kinase Assays for TrkA and Other Receptor Tyrosine Kinases using PathHunter™ Protein-Protein Interaction Technology

The PathHunter™ technology from DiscoveRx is an adaptation of Enzyme Fragment Complementation (EFC) that provides a novel, generic cell-based assay…

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