Scientific Posters
Showing 61–71 of 71 results
The pattern of intracellular signaling downstream of GPCR activation is now known to be specific to the ligand-receptor pair as…
Read MoreAn assay platform that robustly and sensitively quantifies the kinetics of endogenous protein turnover is crucial for discovery of disease-relevant…
Read MoreDenosumab (Prolia®) is a fully human sequence derived monoclonal antibody used for the treatment of osteoporosis in menopausal women via…
Read MoreOne of the major bottlenecks in the development of biosimilars is the need for good bioassays to create potency, stability…
Read MoreSuccess of ADCC assays is highly dependent on the quality of effector cells used. However, human primary cells (such as…
Read MoreDiscoveRx has developed a panel of over 30 naturally Gq-coupled or dual coupled GPCR/Arrestin cell lines that can be used…
Read MoreAntibody-dependent cell-mediated cytotoxicity (ADCC) is the mechanism by which many Class I therapeutic antibodies, including rituximab and trastuzumab, achieve clinical…
Read MoreAssays that directly detect compound binding inside cells can be of great utility in translating in vitro data to more…
Read MoreDiscoveRx has developed a unique assay technology based on an enzyme-coupled detection system that measures ADP accumulation which has been…
Read MoreThe screening and functional characterization of novel ligands for G-protein-coupled receptors (GPCRs) remains a key activity in drug discovery process.…
Read MoreHere, we present data for the ready-to-use PathHunter® Checkpoint assays that target clinically relevant co-inhibitory and co-stimulatory checkpoint receptors and…
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