Scientific Posters

Showing 1–12 of 70 results

Scientific Posters Comprehensive Cell-based Assays for Characterization & Development of Agonistic Antibodies as Therapeutics for Cancer & Autoimmune Diseases

Case studies on the characterization & clinical development of agonistic antibody therapeutics targeting checkpoint receptors.

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Scientific Posters Implementing MOA-Reflective ADCC Assays using Ready-to-Use KILR Target and Effector Cells from Screening to Lot Release

The clinical success of an ever-increasing array of biologics has led to the development of a wide spectrum of immunomodulatory…

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Scientific Posters [Wall Poster] The Druggable GPCRome

DiscoveRx offers an industry-leading portfolio of over 600 naturally coupled human and ortholog G-protein coupled receptor (GPCR) cell lines designed…

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Scientific Posters Unique Properties of PathHunter® β-Arrestin Assays for GPCR Antagonist Discovery and Characterization

A common feature of 7TM receptors is that upon activation, the receptors are bound by cellular Arrestin proteins. DiscoveRx has…

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Scientific Posters Ultrasensitive, 3456 or 1536-Well Miniaturization-Friendly Chemiluminescent Detection of PathHunter® Cell-Based GPCR and Kinase Assays

DiscoveRx’s PathHunter® platform is a simple, cell-based, chemiluminescent assay format that allows for screening large numbers of small molecules or…

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Scientific Posters Utilisation of the InCELL Hunter™ Target Engagement Cell-Based Assay for Profiling of ULK1 Inhibitors

Drug efficacy and cellular target engagement studies have traditionally been monitored by evaluation of downstream cellular responses, such as detection…

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Scientific Posters Utilization of PathHunter® Arrestin Cell Lines for Detection of Arrestin Biased Ligands and Compound Pharmacology Distinct from Second Messengers

DiscoveRx has developed a panel of over 120 characterized GPCR cell lines that monitor receptor activity using interaction with human…

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Scientific Posters Validated Bioassays for Potency, Stability and Lot Release Testing of Biopharmaceuticals

Biologics represents one of the fastest growing classes of biopharmaceutical molecules today. One of the major bottlenecks in the development…

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Scientific Posters Validated Cell-Based Assays for Rapid Screening and Functional Characterization of Therapeutic Monoclonal Antibodies

Monoclonal antibodies (MAbs) represent one of the fastest growing classes of biotherapeutic molecules today. While many technologies exist for generating…

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Scientific Posters Accelerate Drug Development of GLP-1 & -2 Receptor Analogs with Ready-to-Use Cell-Based Assays

There is an increasing need to generate therapeutics targeting metabolic and gastrointestinal diseases to address the global burden of metabolic…

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Scientific Posters Comprehensive & Fit-For-Purpose Solutions to Enable Drug Development for Cytokine Targets

Interleukins are known for their involvement in functioning of both the adaptive and innate immune systems. Interleukins direct immune cells…

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Scientific Posters Robust and Simple Potency and NAb Bioassays for Avastin® Biosimilar Development

One of the major bottlenecks in the development of biosimilars is the need for good bioassays to create potency, stability…

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