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Application Notes InCELL Pulse Cellular Target Engagement Assays for Characterizing Novel Small Molecule Inhibitors of Oncogenic SHP2 Variants

SHP2 (Src-homology 2 domain-containing phosphatase 2) is a protein tyrosine phosphatase encoded by the human PTPN11 gene.SHP2 is a key…

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Scientific Posters Improved Cell-Based Assays To Assess Therapeutic Molecules Against Immune Checkpoint Receptors Such As PD-1, PD-L1 and PD-L2

Regulation of immune responses is tightly controlled through a balance of co-stimulatory and inhibitory checkpoint receptors, often exploited by many…

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