Search results: “Ret”

Showing all 11 results

Application Notes Chemiluminescent cAMP Detection Using DiscoverX HitHunter® Kits Compared With TR-FRET Assays

Publications New Screening Strategy and Analysis for Identification of Allosteric Modulators for GLP-1 Receptor Using GLP-1(9-36)amide.

The glucagon-like peptide-1 receptor (GLP-1R) is an important physiologic regulator of insulin secretion and a major therapeutic target for diabetes…

Publications Identification of resolvin D2 receptor mediating resolution of infections and organ protection.

Endogenous mechanisms that orchestrate resolution of acute inflammation are essential in host defense and the return to homeostasis. Resolvin (Rv)D2…

Blogs & Articles Evaluate GLP-1R Targeted Therapeutics using First-to-Market Semaglutide Qualified GLP-1R Bioassay

Glucagon-Like Peptide-1 (GLP-1), a member of the glucagon-secretin peptide family, is secreted from L-cells of the small intestine and binds…

Blogs & Articles Accelerating Development of GLP-1 & GLP-2 Therapeutics with Validated Bioassays

Glucagon-like peptides, GLP-1 & GLP-2, are well-researched, metabolically significant peptide hormones secreted from the L-cells of the small intestine in…

Videos Pharmacotrafficking Assays

Learn about PathHunter pharmacotrafficking assays to identify small molecule compounds that rescue disease relevant mutant membrane proteins like GPCRs, ion…

Watch Now

Scientific Posters Qualified, Fit-for-Purpose Bioassays for Liraglutide and Exenatide as Frozen Ready-to-Use Cells

With more than 25% of the world’s population diagnosed with type II diabetes and/or metabolic syndrome, the requirement for cost…

Scientific Posters Multi-Parameter GPCR Screening: An Essential Tool for Uncovering GPCR Mutant Phenotypes

The recent appreciation of functional selectivity/ligand bias in GPCR signaling has uncovered new opportunities for therapeutic discovery and continues to…

Scientific Posters Novel Trafficking Assays for Pharmacochaperone Discovery Using Enzyme Fragment Complementation

DiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…

Scientific Posters Novel Trafficking Assays For Pharmacochaperone Discovery Using Enzyme Fragment Complementation Applied To CFTR-ΔF508

DiscoveRx® has pioneered a novel enzyme complementation system to monitor cellular events such as protein translocation, protein interactions, and degradation…

Validation Data Example Eurofins DiscoverX Marker Rescue Document

Test For Replication Competent Retrovirus