A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)
Read MoreSearch results: “Met”
Showing 1–12 of 28 results
Translocation and Trafficking of Membrane Proteins
Read MoreHistone modifications are essential in eukaryotic gene expression and regulation, and are driven by histone writer, eraser, and reader proteins.…
Read MoreTherapeutics targeting glucagon-like peptide, GLP-1 and GLP-2, receptors are being developed to address globally prevalent medical disorders for managing diabetes,…
Watch NowThe recent appreciation of functional selectivity/ligand bias in GPCR signaling has uncovered new opportunities for therapeutic discovery and continues to…
Read MoreGLP Cell Lines & Ready-to-Use Assays from Characterization through QC Lot Release
Read MoreGlucagon-like peptides, GLP-1 & GLP-2, are well-researched, metabolically significant peptide hormones secreted from the L-cells of the small intestine in…
Read MoreLearn how KILR® cytotoxicity assays provide a simple, non-radioactive and dye free method to specifically measure target cell death in…
Watch NowIt is well established that ligand binding can protect proteins from thermal denaturation in a cellular milieu; however, the broad…
Watch NowHere we will describe InCELL Pulse™, which uses DiscoverX’s Enzyme Fragment Complementation (EFC) technology to overcome these limitations of current…
Watch NowThere is an increasing need to generate therapeutics targeting metabolic and gastrointestinal diseases to address the global burden of metabolic…
Read MoreWith more than 25% of the world’s population diagnosed with type II diabetes and/or metabolic syndrome, the requirement for cost…
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