Search results: “ICK”

Cell-based assay kits from early discovery to pre-clinical & clinical development to commercial release & stability programs

Stable cell lines, cell pools, frozen cells, & primary effector cells for a broad range of target classes

Kit & reagents for sensitive quantification of biologics or small molecules to provide accurate pharmacology & reproducible results

Recombinant proteins & cell-based assays to identify small molecule inhibitors & modifiers of methyltransferases & bromodomains

Ready-to-use kits for early discovery phases for screening, proof-of-concept, MOA confirmation, or rank-ordering studies

Cell-based assays to measure 2nd messengers (cAMP & calcium), β-arrestin recruitment, receptor internalization, & ligand binding for GPCR targets-based drug…

Fluorescent assays to measure calcium mobilization in cell lines as a direct indication of GPCR or ion channel activation or…

Accurately monitor GPCR activation by biologics or small molecules & detect cellular cAMP production levels for a variety of applications

Universal G-protein independent cell-based assays to quantify GPCR activation based on the recruitment of β-arrestin

High-quality ion channel cell lines for target discovery, hit screening, lead optimization, & safety studies

Enzymes & cell-based functional, binding, & activity assays for kinase targets discovery through development & for QC lot-release testing

Cell-based assays to evaluate activation & translocation of nuclear proteins including nuclear hormone receptors