Showing 1–12 of 219 results
Case studies on the use of cell-based assays that monitor receptor dimerization and signaling reporter activation targeting IL-12, IL-23, IL-15,…
Read MoreCase studies on the characterization & clinical development of agonistic antibody therapeutics targeting checkpoint receptors.
Read MoreJennifer Lin-Jones, Ph.D., Associate Director of Assay Development R&D Department, Eurofins DiscoverX
Read MoreWatch this webinar to discover functional cell-based assays for characterizing novel therapeutics & biosimilars targeting cytokines in inflammation & oncology.
Watch NowStriatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific enzyme that regulates the signaling molecules that control synaptic plasticity and neuronal…
Read MoreThe MAS-related Gq protein-coupled receptor X4 (MRGPRX4) is poorly investigated. MRGPRX4 has been proposed to be involved in pain transmission,…
Read MoreAgonistic Antibodies and the Role of Checkpoint Receptors in Immune Function
Read MoreThe clinical success of an ever-increasing array of biologics has led to the development of a wide spectrum of immunomodulatory…
Read MoreType 2 diabetes (T2D) affects Latinos at twice the rate seen in populations of European descent. We recently identified a…
Read MoreType 2 diabetes (T2D) affects Latinos at twice the rate seen in populations of European descent. We recently identified a…
Read MoreA series of substituted indoles were examined as selective inhibitors of tropomyosin-related kinase receptor A (TrkA), a therapeutic target for…
Read MoreCurrent therapies for chronic pain can have insufficient efficacy and lead to side effects, necessitating research of novel targets against…
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