Blogs & Articles

Information on compound-target engagement obtained from traditional in vitro binding assays differs greatly from that in a physiologically relevant model…

Cellular membrane proteins play important functions in many biological processes. Understanding their roles often requires that these proteins be isolated…

As newer, cutting-edge therapeutic technologies emerge, an increasing need for rapid and reliable screening tools follows.

The COVID-19 pandemic has left us racing against time for remediation. As a result, we have witnessed hundreds of therapeutic…

Importance in Drug Discovery & Development for Quality Testing Programs. GPCR CNR1 Bioassay example.

Therapeutic antibodies that can elicit different applications of cell-mediated cytotoxicity, such as Antibody-Dependent Cell-mediated Cytotoxicity (ADCC) and many other effector…

Cytokines and their receptors have emerged as major drug targets for inflammatory and autoimmune diseases, allergies, and, more recently, in…

Eurofins DiscoverX, in conjunction with Drug Target Review, sponsored and moderated a Bioassay roundtable discussion webinar with group leaders from…

A novel and growing modality in drug discovery has been the application of Targeted Protein Degradation (TPD). TPD involves the…

Glucagon-Like Peptide-1 (GLP-1), a member of the glucagon-secretin peptide family, is secreted from L-cells of the small intestine and binds…

Drugs interact with living physiology; an in vitro assay of drug activity can be considered a snapshot of the full…

GPCRs have long been regarded as a low-hanging fruit drug target as they are conveniently located on the cell surface…