Biological Information | |
---|---|
Background Information: | ZA70 (Tyrosine Protein kinase ZAP-70, 70 kDa zeta-associated protein, Syk-related tyrosine kinase) is a cytosolic protein tyrosine kinase (PTK) and a member of the Syk family of proteins. ZA70 is expressed in human and murine thymocyte subsets, B cells, and peripheral T cell subsets and associates with zeta-chain to undergo tyrosine phosphorylation following TCR stimulation. ZA70 inhibitors may be useful as immunosuppressants.
GenBank L05148 |
Target Class: | Kinase |
Accession Number: | NM_001079.3; NM_207519.1 |
Target Name: | ZAP-70 |
Target Aliases: | ZAP70, ZAP-70, STD, TZK, SRK |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -20°C |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Datasheets
14-404x Datasheet
View Document