| Biological Information | |
|---|---|
| Background Information: | SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. |
| Target Class: | Kinase |
| Accession Number: | NM_015191.1 |
| Target Name: | SIK2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
SIK2, active, 10 ug
N-terminal GST-tagged, recombinant, human SIK2 amino acids 1-276 expressed by baculovirus in Sf21 insect cells. Purified using glutathione agarose.
Datasheets
15-010x Datasheet
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