| Biological Information | |
|---|---|
| Background Information: | The serum/glucocorticoid regulated kinases (SGK1,2,3) are serine/threonine kinases that belong to the AGC (protein kinase A; protein kinase G and protein kinase C) subfamily that includes cAMP and cGMP dependent kinases, PKB and PKC. SGK1 (SGK) is predominately expressed in kidney, liver and pancreas. The catalytic domain of serum/glucocorticoid regulated protein kinase is most similar to PKB and activated via phosphorylation mechanism when cells are stimulated with insulin, IGF1 or serum, or exposed to oxidative stress.
GenBank AF153609 |
| Target Class: | Kinase |
| Accession Number: | NP_005618 |
| Target Name: | SGK1 |
| Target Aliases: | SGK, SGK1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
SGK1 (S422D), unactive
N-truncated (missing N-terminal 59 amino acids), N-terminal 6His-tagged recombinant, human SGK1 fusion protein, containing an S422D mutation.
Datasheets
14-332x Datasheet
View Document