| Biological Information | |
|---|---|
| Background Information: | Rsk2, also known as Ribosomal Protein S6 Kinase A3, is a member of the RSK family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) Signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS).
The protein sequence is identical to that described in GenBank NM_004586 for human RSK2, over residues 2–end. The cDNA however is more closely related to the mouse sequence described in GenBank AY083469. |
| Target Class: | Kinase |
| Accession Number: | NM_004586.2 |
| Target Name: | Rsk2 |
| Target Aliases: | RPS6KA3, CLS, RSK-2, RSK2, p90-RSK2, ISPK1, MRX19, HU-3, pp90RSK2, MAPKAPK1B, HU-2, RSK, S6K-alpha3, ISPK-1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Rsk2/MAPKAP Kinase 1b, active
N-terminal 6His-tagged between Met1 and Pro2 recombinant, human full length RSK2.
Datasheets
14-480x Datasheet
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