| Biological Information | |
|---|---|
| Background Information: | RPTPµ is a receptor protein-tyrosine phosphatase that mediates homotypic cell-cell interactions and plays a role in adipogenic differentiation via modulation of p120 catenin/CTNND1 phosphorylation. Promotes CTNND1 dephosphorylation and prevents its cytoplasmic localization where it inhibits SLC2A4 membrane trafficking. In turn, SLC2A4 is directed to the plasma membrane and performs its glucose transporter function.
GenBank NM_002845 |
| Target Class: | Phosphatase |
| Accession Number: | NM_002845 |
| Target Name: | RPTPµ |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
RPTPµ, active
N-terminal GST-tagged recombinant, human RPTPµ amino acids 879–1184.
Datasheets
14-780x Datasheet
View Document