| Biological Information | |
|---|---|
| Background Information: | Protein kinase Cm (PKCm) is one of the major protein kinase C isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphosphate, the former acting synergistically with Ca2+ to activate protein kinase C (PKC), resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.
GenBank NM_002742 |
| Target Class: | Kinase |
| Accession Number: | NM_002742.2 |
| Target Name: | PKCµ |
| Target Aliases: | PRKD1, PKD, PKCM, nPKC-mu, PRKCM, PKC-mu, nPKC-D1, PKC-MU, PKD1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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PKCmu, active
N-terminal 6His-tagged recombinant, human full length PKCμ.
Datasheets
14-508x Datasheet
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