| Biological Information | |
|---|---|
| Background Information: | Mitogen-activated protein (MAP) kinases are proline-directed protein kinases that mediate the effects of numerous extracellular stimuli on a wide array of biological processes, such as cellular proliferation, differentiation, and death. Three groups of mammalian MAP kinases have been studied in detail: the extracellular signal-regulated kinases (ERK), the c-Jun NH2-terminal kinases (JNK), and the p38 MAP kinases. The p38 MAP kinase group, which includes the isoforms p38a, p38b, p38g and p38d, activates the transcription factors CREB, ATF1, ATF2, CHOP, and MEF-2C. The p38 MAP kinase also activates other protein kinases, such as Mapkap-2, Mapkap-3, and Mnk1/2. |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase; MAPK; p38 Family |
| Accession Number: | NM_002754.3 |
| Target Name: | p38δ/SAPK4 |
| Target Aliases: | MAPK13, MGC99536, PRKM13, SAPK4, p38delta |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -20°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
p38delta/SAPK4, active
GST-tagged recombinant, human full length p38δ/SAPK4 CHK3.
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14-249x Datasheet
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