| Biological Information | |
|---|---|
| Background Information: | MAPK11 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK11 functions are mostly redundant with those of MAPK14. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets. |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase; MAPK; p38 Family |
| Accession Number: | Y14440 |
| Target Name: | p38β2/SAPK2b2 |
| Target Aliases: | MAPK11, p38-2, SAPK2B, SAPK2, PRKM11, P38BETA2, P38B, p38b, p38Beta, p38beta2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -20°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
p38β2/SAPK2b2, unactive
N-terminal GST-tagged, recombinant, full-length, human p38 beta 2/SAPK2b, unactive
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14-244x Datasheet
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