| Biological Information | |
|---|---|
| Background Information: | Mitogen-activated protein kinase (MAPK)-activated protein kinase 3 (MAPKAPK3) mediates multiple p38 MAPK-dependent inflammatory responses. This kinase can be activated in response to cellular stress and pro-inflammatory cytokines through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. p38 MAP kinase, activated through MKK3, is required for the production of inflammatory cytokines by both antigen-presenting cells and CD4+ T cells.
GenBank NM_004635 |
| Target Class: | Kinase |
| Family: | Ser/Thr Kinase |
| Accession Number: | NM_004635.3 |
| Target Name: | MAPKAPK3 |
| Target Aliases: | MAPKAPK3, MAPKAP, MAPKAP3, 3PK, MAPKAPK-3, 3pK |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
MAPKAP Kinase 3, active
N-terminal GST-tagged recombinant, human MAPKAP Kinase 3 amino acids 2-end; activated using SAPK2a (Catalog #14-587).
Datasheets
14-585x Datasheet
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