GRK3, G protein-coupled receptor kinase 3, is a beta-adrenergic receptor kinase that specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]
G Protein-Coupled Receptor Kinase 3BARK2ADRBK2AdrenergicBetaReceptor Kinase 2Beta-ARK-2
Drug Discovery & Development
1 year at -70°C
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GRK3, active, 10 ug
10 µg of active GRK3. C-terminal 6His-tagged, recombinant, full length, human GRK3.