Biological Information | |
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Background Information: | Eph (erythropoietin-producing hepatocellular) family tyrosine kinase receptors consist of two groups: EphA group members respond to ephrin-A, which is anchored to the cell membrane by glycosylphosphatidylinositol, whereas EphB group members respond to ephrin-B, containing a transmembrane domain. Among them, only EphA4 can cross-respond to both ephrin-A and -B. EphB1 (EPHT2, NET, Hek6, ELK) is expressed predominantly in developing neural structures in embryos, in vascular epithelium of kidney and other tissues. EphB1 signals regulation of cell attachment and cell-cell assembly and are implicated in neuronal and vascular cell targeting.
GenBank NM_004441 |
Target Class: | Kinase |
Family: | Receptor Typosine Kinase (RTK): Growth Factor Receptor |
Accession Number: | NM_004441.3 |
Target Name: | EphB1 |
Target Aliases: | EPHB1, Hek6, EPHT2, NET, Elk, FLJ37986, ELK, EphB1, HEK6 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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