DCAMKL2 is a protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. It may play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity).
Drug Discovery & Development
6 months at -70°C
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