| Biological Information | |
|---|---|
| Background Information: | CHAK1 is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function.
GenBank AY032950.1 |
| Target Class: | Kinase |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | ChaK1 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
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ChaK1, active
N-terminal 6His-tagged recombinant, human ChaK1 amino acids 1180-end.
Datasheets
14-961x Datasheet
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