Cdk2/Cyclin A, active

C-terminal 6His-tagged recombinant, human full length cdk2, and N-terminal GST-tagged human full length cyclin A.

Catalog #: 14-448


Biological Information
Background Information:
The cyclin-dependent kinases (CDKs), are a family of serine threonine protein kinases, that control the cell division cycle. In mammals, nine different CDKs (cdk 1 to cdk 9) have been identified. CDKs are regulated on various levels including binding of proteins (cyclins, inhibitors, and assembly factors), protein degradation, transcriptional control, localization, and multiple phosphorylations. This leads to timely regulation of CDK activity, allowing progression from one cell cycle phase to the next. The cdk2 promotes the G1/S transition and progression through the S phase when bound to specific cyclins (E and A). Recent evidences indicate that CDK2 is involved in cell cycle independent functions such as DNA damage repair. EMBL M68520 / EMBL X51688
Target Class:
Serine/Threonine Kinase: CDK1 subfamily
Accession Number:
NM_001798.2; NM_052827.1
Target Name:
Target Aliases:
CDK2, p33(CDK2)
Target Species:
Product Type:
Drug Discovery & Development
Storage Conditions:
6 months at -70°C
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.


14-448x Datasheet

View Document