| Biological Information | |
|---|---|
| Background Information: | Mammalian casein kinase 2α1 (CK2a1) is a highly conserved serine-threonine protein kinase that is constitutively expressed in all eukaryotic cell types including yeast, insects, and vertebrates. The enzyme can utilize GTP or ATP as a phosphate donor. Casein kinase activity is stimulated by mitogens in a cell type-specific manner during development and embryogenesis. Inhibition of CK2α1 may be useful in the treatment of human squamous cell carcinoma, adenocarcinoma of the lung, prostatic hyperplasia and lymphomas.
GenBank J02853.1 |
| Target Class: | Kinase |
| Accession Number: | EMBL J02853 |
| Target Name: | CK2α |
| Target Aliases: | CSNK2A1, CK2A1, CKIIAlpha, CKII, CK2 Subunit Alpha |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -20°C |
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Casein Kinase 2alpha, active
6His-tagged recombinant, human full length Casein Kinase 2α.
Datasheets
14-445x Datasheet
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