| Biological Information | |
|---|---|
| Background Information: | Mammalian casein kinase 1 (CK1, ) gene family consists of seven different genes in mammals, CKIa, b, g1, g2, g3, d and e. These enzymes are important components of signal transduction pathways and regulate cell growth, division and differentiation, and the activities of a variety of oncoproteins and transcription factors. CSNK1D (Casein kinase I delta isoform, CKI-delta, CKId) plays an important role in cell survival and protects regulatory proteins from caspase-mediated degradation in apoptosis. Inhibitors may find clinical use for the treatment of Alzheimer's disease and amyotrophic lateral sclerosis.
GenBank AB063114. This is a rat cDNA that is 100% identical to human casein kinase 1 delta over 1-294 of the predicted amino acid sequence. |
| Target Class: | Kinase |
| Accession Number: | NM_001893.3; NM_139062.1 |
| Target Name: | CK1γδ |
| Target Aliases: | CSNK1D, CKI-delta, HCKID, CKId |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -20°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Casein Kinase 1delta (aa 1-294), active
N-terminal GST-tagged recombinant, human CK1 delta amino acids 1-294.
Datasheets
14-520x Datasheet
View Document