| Biological Information | |
|---|---|
| Background Information: | Calcium/calmodulin dependent protein kinase II (CaMKII) is a serine/threonine kinase which is encoded as over two dozen variants generated by alternative mRNA splicing of 4 genes. CaMKII phosphorylate target proteins in a calcium calmodulin dependent manner and play critical for gene transcription, ion channel activity, cytoskeletal function and carbohydrate metabolism. CaMKII has been implicated in memory and cell growth control as well as in the disorders of cancer, cystic fibrosis, Alzheimer's disease and epilepsy. The overexpression of a specific constitutively active CAMK2D (CaMKIId) in PC-12, P19 and NIH/3T3 cells induces neurite outgrowth.
GenBank NM_172115 |
| Target Class: | Kinase |
| Family: | CAMK2 family |
| Accession Number: | NM_001221.2; NM_172115.1; NM_172127.1; NM_172128.1 |
| Target Name: | CaMKIIδ |
| Target Aliases: | CAMK2D, CAMKD, MGC44911 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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CaM Kinase IIdelta, active
N-terminal 6His-tagged recombinant, human full length CaM Kinase IIδ N-terminal 6His-tagged recombinant, human full length CaM Kinase IIδ.
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14-723x Datasheet
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