| Biological Information | |
|---|---|
| Background Information: | CAM KINASE IIα belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene.
GenBank AF091486.1 |
| Target Class: | Kinase |
| Family: | CAMK2 family |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | CaM Kinase IIa |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
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CaM Kinase IIalpha, active
N-terminal 6His-tagged recombinant, human full length CaM kinase IIα.
Datasheets
14-962x Datasheet
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