| Biological Information | |
|---|---|
| Background Information: | SUV4-20H2 (Suppressor of variegation 4-20 homolog 2) is a histone methyltransferase that adds methyl groups to histone H4 lysine 20 (H4K20), leading to the formation of the repressive chromatin mark H4K20me2 and H4K20me3. SUV4-20H2 is one of two paralogs of SUV4-20H family, which also includes SUV4-20H1. SUV4-20H2 is involved in the regulation of various cellular processes, including DNA damage response, heterochromatin formation, and telomere maintenance. It has been shown to play a role in the recruitment of DNA damage response factors to chromatin after DNA damage, and in the establishment of heterochromatin domains at repetitive DNA sequences, including telomeres.
SUV4-20H2 is an important histone methyltransferase that plays a critical role in the regulation of gene expression and the maintenance of chromatin structure. |
| Target Class: | Epigenetic Protein |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | SUV4-20H2 |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
SUV4-20H2
Recombinant human SUV4-20H2 amino acids 2-248.
Datasheets
EPI067 Datasheet
View Document