| Biological Information | |
|---|---|
| Background Information: | The PrecisION® hNav1.5 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Nav1.5 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Nav1.5 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Voltage-Gated Sodium Ion Channel |
| Accession Number: | NM_000335 |
| Target Name: | Nav1.5 |
| Target Aliases: | cardiac sodium channel, Skm2, SkMII, sodium channel protein type 5, sodium channel, voltage-gated, type V, alpha subunit, sodium channel, voltage gated, type V alpha subunit, sodium channel |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hNav1.5 Recombinant Stable Cell Line
The PrecisION® hNav1.5 Recombinant Stable Cell Line measures Nav1.5 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
View DocumentDatasheets
CYL3004 Datasheet
View Document