| Biological Information | |
|---|---|
| Background Information: | The PrecisION® hKv2.1/hKv9.2 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying Kv2.1/Kv9.2 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses Kv2.1/Kv9.2 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Voltage-Gated Potassium Ion Channel |
| Accession Number: | hKv2.1 Sequence: (Accession Number NM_004975); hKv9.2 Sequence: (Accession Number NM_020697) |
| Target Name: | Kv2.1/Kv9.2 |
| Target Aliases: | Kv2.1: DRK1, Shab, delayed rectifier potassium channel 1, potassium voltage-gated channel subfamily B member 1, potassium voltage-gated channel, Shab-related subfamily, member 1, potassium channel, voltage gated Shab related subfamily B, member 1, potassium channel, voltage gated Shab-related subfamily B, member 1, potassium voltage gated channel KV9.2: delayed-rectifier K(+) channel alpha subunit 2, potassium voltage-gated channel, modifier subfamily S, member 2, potassium voltage-gated channel, K+ voltage-gated channel, subfamily S, 2, K+ voltage-gated channel |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hKv2.1/hKv9.2 Recombinant Stable Cell Line
The PrecisION® hKv2.1/hKv9.2 Recombinant Stable Cell Line measures Kv2.1/Kv9.2 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
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CYL3067 Datasheet
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