| Biological Information | |
|---|---|
| Background Information: | The PrecisION® hKCNQ1/hminK Recombinant Stable Cell Line is a stable, engineered cell line for use in studying KCNQ1/hminK ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses KCNQ1/hminK ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Voltage-Gated Potassium Ion Channel |
| Accession Number: | AF000571 |
| Target Name: | KCNQ1/hminK |
| Target Aliases: | JLNS1, IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1, RWS1, Romano-Ward syndrome 1, KCNA8 , KCNA9, LQT1, slow delayed rectifier, potassium channel, voltage gated KQT-like subfamily Q, member 1, potassium channel, voltage-gated KQT-like subfamily Q, member 1, potassium voltage-gated channel |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hKCNQ1/hminK Recombinant Stable Cell Line
The PrecisION® hKCNQ1/hminK Recombinant Stable Cell Line measures KCNQ1/hminK ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
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CYL3007 Datasheet
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