| Biological Information | |
|---|---|
| Background Information: | The PrecisION® hHCN1 Recombinant Stable Cell Line is a stable, engineered cell line for use in studying HCN1 ion channels, including drug candidates which affect channel function. This cell line enables assessment of ion channel function via detection of electrophysiological signals. The included cell line overexpresses HCN1 ion channels. Upon ligand/agonist induced channel activation, response can be detected via automated or manual electrophysiological techniques. This stable modified cell line is provided as two vials of cryopreserved cells. |
| Target Class: | Ion Channel |
| Family: | Voltage-Gated Potassium Ion Channel |
| Accession Number: | NM_021072 |
| Target Name: | HCN1 |
| Target Aliases: | BCNG1, HAC2, hyperpolarization activated cyclic nucleotide-gated potassium channel 1, hyperpolarization-activated, cyclic nucleotide-gated K+ 1, hyperpolarization-activated |
| Target Species: | Human |
| Usage | |
| Product Type: | Stable Cell Lines |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store in vapor phase of liquid nitrogen. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Electrophysiology |
| Additional Information | |
| Brand: | PrecisION® |
PrecisION® hHCN1 Recombinant Stable Cell Line
The PrecisION® hHCN1 Recombinant Stable Cell Line measures HCN1 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
User Manuals & Protocols
70-430 PrecisION Ion Channel Cell Lines_Rev_2.0
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CYL3040 Datasheet
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