PathHunter® eXpress RXFP3 CHO-K1 β-Arrestin GPCR Assay

The PathHunter® eXpress RXFP3 CHO-K1 β-Arrestin GPCR Assay measures RXFP3 (GPCR) activity via recruitment of β-Arrestin 2. eXpress kits contain all assay materials: cells, reagents, and plates.

Catalog #: 93-0692E2CP2L


Biological Information
Background Information:
The PathHunter® RXFP3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. relaxin-3) based activation of RXFP3 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology. The cells included overexpress PK-tagged RXFP3 and EA-tagged β-Arrestin-2. Activation of RXFP3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.
Target Class:
Relaxin Family Peptide Receptors
Sub Family:
Class A
Accession Number:
Target Name:
Target Aliases:
Relaxin family peptide receptor 3, G-protein coupled receptor GPCR135, G-protein coupled receptor SALPR, GPCR135, RLN3 receptor 1, RLN3R1, RXFPR3, SALPR, g protein-coupled receptor SALPR, relaxin 3 receptor 1, relaxin family peptide receptor 3, relaxin-3 receptor 1, relaxin/insulin-like family peptide receptor 3, somatostatin and angiotensin-like peptide receptor, somatostatin- and angiotensin-like peptide receptor
Target Species:
Cell Background:
Product Type:
eXpress Assay Kits
Drug Discovery & Development
Storage Conditions:
Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
Ready-to-use eXpress assay kits are intended for in vitro research purposes only. These kits are not suitable for lot release applications. Refer to the ready-to-use bioassay kit format for potency testing in lot release for biologic therapeutics. These products may be covered by issued US and/or foreign patents, patent applications and subject to a Limited Use Label License. Please visit for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Type:
β-Arrestin isoform:
Assay Measures:
β-Arrestin Recruitment
Detection Method:
Additional Information

User Manuals & Protocols

70-255 PathHunter B Arrestin eXpress GPCR Assay REV4 User Manual

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93-0692E2x Datasheet

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