| Biological Information | |
|---|---|
| Background Information: | JMJD2A (Jumonji domain-containing protein 2A) is an epigenetic protein that functions as a histone demethylase. It is responsible for removing methyl groups from specific lysine residues on histones, leading to the formation of euchromatin and activation of gene expression. JMJD2A is widely expressed in many tissues and is important for normal development and cellular function. It is involved in various biological processes, including transcriptional regulation, DNA damage response, and cell cycle progression.
Aberrant JMJD2A activity has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular diseases. JMJD2A inhibitors are being developed for therapeutic purposes, and understanding its function is important for developing new therapies. |
| Target Class: | Epigenetic Protein |
| Accession Number: | Refer to CoA for Accession Number |
| Target Name: | JMJD2A |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 1 year at -70°C |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
JMJD2A
N-terminal 6His-tagged recombinant amino acids 1-359, human JMJD2A.
Datasheets
EPI029 Datasheet
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