| Biological Information | |
|---|---|
| Background Information: | The ChemiScreen™ CXCR4 Chemokine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CXCR4 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1mL of 1mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. |
| Target Class: | GPCR |
| Family: | Chemokine Receptors |
| Accession Number: | M99293 |
| Target Name: | CXCR4 (SDF-1R) |
| Target Aliases: | Chemokine (C-X-C motif) receptor 4, CXCR4, CXCR4, Chemokine |
| Target Species: | Human |
| Cell Background: | Chem-1 |
| Usage | |
| Product Type: | Membrane Preparations |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Vial to be stored at -70°C. Avoid repeat freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Assay Information | |
| Assay Measures: | Binding |
| Detection Method: | FluorescenceRadioactivity |
| Additional Information | |
| Brand: | ChemiSCREEN™ |
ChemiScreen™ CXCR4 Chemokine Receptor Membrane Preparation
The ChemiScreen™ CXCR4 Chemokine Receptor Membrane Preparation measures ligand binding to CXCR4 GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.
Datasheets
HTS004M Datasheet
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