| Biological Information | |
|---|---|
| Background Information: | CTLA4, or CTLA-4 is also known as cytotoxic T-lymphocyte-associated protein 4 or CD152. This monoclonal antibody binds human CTLA4, which functions as a immune checkpoint receptor that downregulates the immune system. CTLA4 is expressed on activated T cells and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), and the protein restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. Provided as 100 μg of antibody in buffer. |
| Target Class: | Checkpoint Receptor |
| Family: | IgSF (immune inhibitory Receptor) |
| Target Name: | CTLA4 |
| Usage | |
| Product Type: | Antibodies |
| Application: | Drug Discovery & Development |
| Storage Conditions: | Store at -20°C. Please avoid multiple freeze/thaw cycles. |
| Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
| Additional Information | |
| Brand: | DiscoverX |
Anti-CTLA4 Antibody [14D3]
Anti-CTLA4 Antibody [14D3] is an antibody acting as an antagonist for CTLA4 and CD86. This product is provided as 100μg of antibody in buffer.
Datasheets
92-1319 Datasheet
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