Biological Information | |
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Background Information: | TAE684 (NVP-TAE684) is a synthetic potent and selective inhibitor of the kinase ALK (IC50=3nM) as well as FLT3 and TIE2 (IC50=3nM and 12nM, respectively). It is 100 times more selective for ALK than InsR, and is effective at inhibiting the NPM-ALK fusion protein responsible for survival and proliferation of anaplastic large-cell lymphomas (ALCLs). Provided as 5 mg of dry powder. |
Target Name: | TAE684 |
Usage | |
Product Type: | Control Ligands & Inhibitors |
Application: | Drug Discovery & Development |
Storage Conditions: | Store at ≤-20°C. Please avoid multiple freeze/thaw cycles. |
Usage Disclaimer: | These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information. |
Additional Information | |
Brand: | DiscoverX |
TAE684
TAE684 is an inhibitor of ALK. This product is provided as 5 mg of dry powder.
Datasheets
92-1185 Datasheet
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