| Biological Information | |
|---|---|
| Background Information: | eEF-2K is a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.
GenBank NM_013302. The recombinant protein contains the amino acid substitution H23R with reference to NM_013302. This conflict is reported in GenBank BC032665 and EST BM469975. |
| Target Class: | Kinase |
| Accession Number: | NM_013302.3 |
| Target Name: | eEF-2K |
| Target Aliases: | EEF2K, MGC45041, HSU93850, eEF-2K |
| Target Species: | Human |
| Usage | |
| Product Type: | Enzymes |
| Application: | Drug Discovery & Development |
| Storage Conditions: | 6 months at -70°C |
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eEF-2K, active
N-terminal GST-tagged recombinant, human eEF-2K amino acids 2-end.
Datasheets
14-654x Datasheet
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