PathHunter® β-Arrestin2 Retroparticles

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The PathHunter® β-Arrestin2 Retroparticles are retroparticles for transducing cells with β-Arrestin2-EA to allow for arrestin recruitment assays. This product contains 4 vials of cryopreserved retroparticles.

Catalog #: 93-1087 Size: 4 vials x 0.5 mL

$3,479.00

Biological Information
Background Information:
The PathHunter® β-Arrestin2 Retroparticles are MMLV particles designed to transduce cells of interest with β-Arrestin2 fused to EA. In conjunction with a plasmid expressing a PK-tagged GPCR of interest, this allows for these cells to be used for β-Arrestin2 recruitment assays. This product uses EFC technology (https://www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). Ligand induced recruitment of β-Arrestin2 to the activated GPCR leads to complementation and produces EFC signal. These retroparticles ship as 4 vials of cryopreserved retroparticles.
Target Class:
GPCR
Usage
Product Type:
Retroparticles
Application:
Drug Discovery & Development
Storage Conditions:
Short term (24 h): Store in vapor phase of liquid nitrogen.
Usage Disclaimer:
These products may be covered by issued US and/or foreign patents, patent application and subject to Limited Use Label License. Please visit discoverx.com/license for a list of products that are governed by limited use label license terms and relevant patent and trademark information.
Assay Information
Assay Measures:
β-Arrestin Recruitment
Detection Method:
Chemiluminescence
Additional Information
Brand:
PathHunter®

User Manuals & Protocols

70-374 PathHunter Beta-Arrestin2 Retroparticles REV2 User Manual

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Datasheets

93-1087 Datasheet

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