Biological Information | |
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Background Information: | The ERBB family of receptor tyrosine kinases, namely the EGF receptor (EGFR), ERBB2/HER2/Neu, ERBB3, and ERBB4, regulate cellular proliferation, differentiation, and programmed cell death in a growth factor-dependent manner. ERBBs mediate signaling by a large number of growth factors that are structurally related to EGF such as transforming growth factor-a or amphiregulin.
GenBank NM_005235 |
Target Class: | Kinase |
Family: | Receptor Typosine Kinase (RTK): Growth Factor Receptor |
Accession Number: | NM_001005915.1; NM_001982.2 |
Target Name: | ErbB4 |
Target Aliases: | ERBB4, HER4 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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