Safety & Toxicology Webinar Series
Improving compound safety and investigational toxicology outcomes
DiscoverX® offers an unprecedented global view of therapeutic selectivity, mechanism of action and safety pharmacology comprehensive portfolio of target-based and BioMAP® primary human cell systems. In this webinar series we showcase some of the different applications of our screening and profiling services to identify potential off-target liabilities, predict potential tox mechanisms and more.
Webinars will continue to be added to this series, so please check back often.
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| May 19, 2017 |
SAFETYscan: オフターゲット効果を機能アッセイで同定,GPCR・チャネル・キナーゼ等を一気にスクリーニング - 60 min.
What will be covered?
- 全てのヒトのターゲットで安全性を確認
- 通常の結合データを上回る機能データ
- アッセイ開発のコストと時間を削減
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| May 25, 2016 |
Webinar: A Phenotypic Platform for Characterization of Drug Safety Mechanisms in Human Primary Cell Disease Models - 40 min.
What will be covered?
- How to maximize knowledge of your compounds using the BioMAP® Diversity PLUS™ panel of human primary cells systems
- How to understand mechanism classification analysis and toxicity signatures
- A case study on discovery of a mechanism-based novel signature for skin irritation
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| March 3, 2015 |
BioMAP® Systems for Investigative Toxicology & Safety Assessment: A chemical biology approach for elucidating mechanisms of adverse drug reactions in human primary cell disease models - 40 min.
What will be covered?
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Introduction to the BioMAP Technology Platform
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Discussion of the challenges of building high throughput, physiologically relevant assays
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Description of methods for analysis of large, phenotypic assay data sets
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Case study: the discovery of a novel mechanism underlying thrombosis-related side effects
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| April 3, 2014 |
BioMAP® Systems for Investigative Toxicology & Safety Assessment - 60 min.
What will be covered?
• Overview of the BioMAP® platform
• Case studies relevant to safety assessment
• Compound Profiling Services using the Predictive Tox panel |
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