BioMAP℠ Webinar Series
BioMAP® - solutions for phenotypic drug discovery
In this webinar series, we showcase how to apply the unique BioMAP platform of predictive human-based models to the discovery and development of safer and more efficacious therapeutics and chemicals. BioMAP profiles provide actionable data to guide lead selection, lead optimization (SAR), mechanistic understanding of compound action, and nomination of candidates for preclinical development. Topics covered include general technology overview as well as focused topics covering introduction and overview, data analysis, oncology, safety and toxicology and more.
Webinars will continue to be added to this series, so please check back often.
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| September 8, 2017 |
BioMAPが今アツイ! 医療抗体などが騒がれている中で、低分子化合物も活躍?! - 60 min.
What will be covered?
- 世界で唯一：プライマリー細胞を使用した、ガンの微小細胞環境モデル
- 話題となっている免疫チェックポイント阻害剤の評価例
- 医療抗体の中でも低分子化合物が活躍？
- BioMAPシステムの応用例
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| April 19, 2017 |
Webinar: Combining Target-Based and Phenotypic Discovery Assays for Drug Repurposing - 40 min.
What will be covered?
- Using phenotypic profiling to characterize clinically successful drugs for a given indication
- Combining target-based and phenotypic data to prioritize drugs for repurposing
- Understanding how multi-targeted kinases can be pivoted towards new indications
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| October 26, 2016 |
Webinar: Target to Phenotype: Tools to Accelerate Your Immuno-Oncology Drug Pipeline - 60 min.
What will be covered?
- Challenges in immuno-oncology drug development
- Tools to expedite and simplify any immuno-oncology drug development pipeline
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| September 30, 2016 |
Webinar: Immuno-Oncology Drug Development: Profiling Immunomodulatory Biologics and Compounds in Human Primary Cell-Based Oncology Models - 60 min.
What will be covered?
- Overview of the BioMAP® immuno-oncology/oncology systems
- Information BioMAP iOnc studies provide
- Host stromal/vascular - tumor microenvironment biology
- Case studies of profiling Ab therapies (anti-PD-1, anti-CTLA-4, etc.) and preclinical compounds
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| August 10, 2016 |
Webinar: New Tricks for Old Drugs: An Unbiased Phenotypic Approach to Drug Repurposing - 40 min.
What will be covered?
- Overview of the BioMAP Diversity PLUS phenotypic screening platform's modeling of broad human tissue and disease biology
- Details of how Diversity PLUS profiling guides new indications for marketed drugs and pre-clinical candidates
- Examples highlighting how this technology is used to support repositioning of approved drugs for alternate indications
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| April 22, 2016 |
BioMAP表現型プロファイリング：今まで見えなかった試験物質の一面を明瞭に - 60 min.
What will be covered?
- Tofacitinibの様な抗炎症剤から、食材までの表現型解析例の紹介
- 臨床試験への架け橋となったデータの実施例
- Skin Rash・Thrombosis等を明瞭に：BioMAPシステムの応用例
- パワーアップした試験報告書のご紹介：さらに充実したデータのご提供
- メカニズム探査によるリード化合物の毒性、薬理、安全性等の同定
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