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BioMAP℠ Webinar Series

BioMAP® -  solutions for phenotypic drug discovery

In this webinar series, we showcase how to apply the unique BioMAP platform of predictive human-based models to the discovery and development of safer and more efficacious therapeutics and chemicals. BioMAP profiles provide actionable data to guide lead selection, lead optimization (SAR), mechanistic understanding of compound action, and nomination of candidates for preclinical development. Topics covered include general technology overview as well as focused topics covering introduction and overview, data analysis, oncology, safety and toxicology and more.
 
Webinars will continue to be added to this series, so please check back often.

 


Event Date ▼ Event Name PDF Link Webinar Link
April 19, 2017 Webinar: Combining Target-Based and Phenotypic Discovery Assays for Drug Repurposing - 40 min.

What will be covered?

  • Using phenotypic profiling to characterize clinically successful drugs for a given indication
  • Combining target-based and phenotypic data to prioritize drugs for repurposing
  • Understanding how multi-targeted kinases can be pivoted towards new indications
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October 26, 2016 Webinar: Target to Phenotype: Tools to Accelerate Your Immuno-Oncology Drug Pipeline - 60 min.

What will be covered?

  • Challenges in immuno-oncology drug development
  • Tools to expedite and simplify any immuno-oncology drug development pipeline
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September 30, 2016 Webinar: Immuno-Oncology Drug Development: Profiling Immunomodulatory Biologics and Compounds in Human Primary Cell-Based Oncology Models - 60 min.

What will be covered?

  • Overview of the BioMAP® immuno-oncology/oncology systems
  • Information BioMAP iOnc studies provide
  • Host stromal/vascular - tumor microenvironment biology
  • Case studies of profiling Ab therapies (anti-PD-1, anti-CTLA-4, etc.) and preclinical compounds
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August 10, 2016 Webinar: New Tricks for Old Drugs: An Unbiased Phenotypic Approach to Drug Repurposing - 40 min.

What will be covered?

  • Overview of the BioMAP Diversity PLUS phenotypic screening platform's modeling of broad human tissue and disease biology
  • Details of how Diversity PLUS profiling guides new indications for marketed drugs and pre-clinical candidates
  • Examples highlighting how this technology is used to support repositioning of approved drugs for alternate indications
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April 22, 2016 BioMAP表現型プロファイリング:今まで見えなかった試験物質の一面を明瞭に - 60 min.

What will be covered?

  • Tofacitinibの様な抗炎症剤から、食材までの表現型解析例の紹介
  • 臨床試験への架け橋となったデータの実施例
  • Skin Rash・Thrombosis等を明瞭に:BioMAPシステムの応用例
  • パワーアップした試験報告書のご紹介:さらに充実したデータのご提供
  • メカニズム探査によるリード化合物の毒性、薬理、安全性等の同定
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December 11, 2015 Introduction to BioMAP® Systems: Phenotypic drug profiling in human primary cell systems - 60 min.

What will be covered

  • How BioMAP systems creates a unique profile for your drug
  • Case studies using the screening technology platform
  • Applications for phenotypic drug discovery
  • Services offered for compound profiling
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November 6, 2015 被験化合物によるGi ToxやSkin Rash等を明瞭に:BioMAPシステムの応用例 - 60 min.

eSeminarの課題:

  • Gi Tox、Skin Rash等の応用実施例の紹介
  • リード化合物の選択や臨床標準治療との直接比較
  • メカニズム探査によるリード化合物の毒性、薬理、安全性等の同定
  • 2016年度パネルスケジュール
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July 9, 2015 Profiling Immunomodulatory mAbs, Compounds and Combinations in Human Primary Cell-based Oncology Models - 30 min.

What will be covered

  • Overview of the BioMAP Immuno-Oncology/Oncology Systems
    • Host Stromal/Vascular - Tumor Microenvironment Biology
    • Inflammation/Immune Biology
    • Comparison to MLR (Mixed Lymphocyte Reaction) assays
    • Immunophenotypic analysis
  • Case studies of profiling Ab therapies (anti-PD-1, anti-CTLA-4, etc.) and preclinical compounds
  • Case studies of combination studiest
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April 1, 2015 BioMAP® Systems: Human Primary Cell Based Disease and Tissue Models for Drug Discovery - 40 min.

What will be covered?

  • Overview of BioMAP® Technology Platform
  • Case studies and applications of phenotypic screening in drug discovery
  • Services offered for compound profiling
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February 19, 2015 Human Primary Cell BioMAP® Systems for Drug Discovery - 60 min.

What will be covered?

  • Overview of the BioMAP systems
  • Case studies using the screening technology platform
  • Applications for phenotypic drug discovery
  • Services offered for compound profiling
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September 25, 2014 Analysis of α-PD-1, α-PD-L1 and Yervoy® (ipilimumab/α-CTLA-4) Immune Check Point Antibodies in Human Primary Cell BioMAP® Oncology Systems - 53 min.

What will be covered

  • Overview of the BioMAP Oncology Systems
  • Case studies of immune check point antibodies using the screening technology platform
  • Applications for phenotypic drug discovery and compound profiling
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July 31, 2014 BioMAP Webinar: Human Primary Cell BioMAP® Systems for Drug Discovery - 60 min.

What will be covered?

• Overview of the BioMAP systems
• Case studies using the screening technology platform
• Applications for phenotypic drug discovery
• Services offered for compound profiling
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August 14, 2013 BioMAP® Systems: Human Primary Cells Systems for Phenotypic Drug Discovery - 60 min.

What will be covered?

  • Overview of the BioMAP systems
  • Case studies using the screening technology platform
  • Applications for phenotypic drug discovery
  • Services offered for compound profiling
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July 26, 2013 Introduction to the BioMAP® Platform: Primary Human Cell Systems for Drug Discovery - 60 min.

What will be covered?

We will introduce the BioMAP Platform and present examples of how the primary human cell-based systems have provided insights into the drug discovery and development process, as well as enable biomarker discovery and validation.
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February 14, 2013 Introduction to the BioMAP® Platform: Primary Human Cell Systems for Drug Discovery - 60 min.

What will be covered?

• Overview of the BioMAP system
• Case Studies using the platform
• Compound Profiling Services
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