Kappa agonist CovX-Bodies.

Authors: Roberts LR, Brady K, Brown A, Davey D, Feng L, Huang H, Liu D, Malet L, McMurray G, Phelan A, Saunders K and Bhat A.
Publisher/Year: Bioorg Med Chem Lett 22(12):4173-8.
Pub Med ID/Journal ID: PMID:22583618

Abstract

Small peptidic kappa agonists were covalently linked to the reactive lysine of the CovX antibody to create compounds having potent activity at the kappa receptor with greatly extended half-life when compared to the parent peptide as exemplified by compound 20.