[User Manual] cAMP Hunter™ Gs and Gi Cell Lines

[User Manual] cAMP Hunter™ Gs and Gi Cell Lines

File Name/Number:


cAMP Hunter Cell Lines are non-force-coupled Gs and Gi stable clonal cell lines that expedite drug screening by providing robust responses, with accurate pharmacology. They provide the means for the measurement of an ubiquitous second messenger (cAMP) to determine the mechanism of action of ligands. Each cell line has been characterized for its appropriate GPCR pharmacology, specificity, and stability in culture and can be effectively used for screening both biologics and small molecules. For detection of cAMP, the cAMP Hunter Cell Lines can be paired with DiscoverX's HitHunter cAMP Assays for Small Molecules or Biologics.