Biological Information | |
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Background Information: | NEK9 (NIMA-related kinase 9) is a serine/threonine protein kinase that belongs to the NEK (never in mitosis gene A-related kinase) family of kinases. It is involved in a variety of cellular processes, including regulation of the cell cycle, mitosis, and the DNA damage response.
NEK9 is expressed in a wide range of tissues and cell types, and is regulated by various post-translational modifications, including phosphorylation and ubiquitination.
Research has suggested that NEK9 plays a role in several diseases, including cancer and ciliopathies. In cancer, NEK9 has been shown to promote cell proliferation and survival, and inhibition of NEK9 has been suggested as a potential cancer therapy. In ciliopathies, NEK9 has been implicated in the regulation of cilia length and number, and mutations in NEK9 have been associated with ciliopathy-related disorders such as Joubert syndrome. |
Target Class: | Kinase |
Accession Number: | NM_033116 |
Target Name: | NEK9 |
Target Aliases: | NEK9 |
Target Species: | Human |
Usage | |
Product Type: | Enzymes |
Application: | Drug Discovery & Development |
Storage Conditions: | 6 months at -70°C |
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