Targets / Kinase / HCK
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Hemopoietic cell kinase (HCK)

Target Class
Kinase
Family
Cytosolic tyrosine kinase
Official Symbol
HCK
Species
Human
Accession Number
NM_002110.2
Alias Names
JTK9; hematopoietic cell kinase; hemopoietic cell kinase; p59-HCK/p60-HCK; p59Hck; p61Hck; tyrosine-protein kinase HCK
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]
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Solution Portfolio

Related Group Members: Cytosolic tyrosine kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Cell Lines
Assay Measures Background Species Cell Line
Intracellular Binding U2OS 96-0041C15
Ready to Use eXpress Kits
Assay Measures Background Species Assay Kit
Intracellular Binding A549 96-0041E15CP0M
Intracellular Binding A549 96-0041E15CP0L
LeadHunter Screening & Profiling Services
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
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