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Ephrin type-B receptor 3 (EphB3)

Target Class
Kinase
Family
Receptor Tyrosine Kinase
Official Symbol
EphB3
Species
Human
Accession Number
NM_004443.3
Alias Names
EK2; EPH receptor B3; EPH-like kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; ETK2; EphB3; HEK2; TYRO6; embryonic kinase 2; ephrin type-B receptor 3; human embryo kinase 2; tyrosine-protein kinase TYRO6
Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into two groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. This gene encodes a receptor for ephrin-B family members. [provided by RefSeq, Mar 2010]
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Solution Portfolio

Related Group Members: Receptor Tyrosine Kinase
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DiscoveRx offers cell-based assays that target other members of this gene family or functional group. Click on the family name to browse all available assays for that target family


Assay Measures Background Species Cell Line
Receptor Phosphorylation U2OS Human 93-0842C3
Assay Measures Background Species Assay Kit
Receptor Phosphorylation U2OS Human 93-0842E3CP16S
Receptor Phosphorylation U2OS Human 93-0842E3CP16M
Receptor Phosphorylation U2OS Human 93-0842E3CP16L
KINOMEscan TKscan BROMOscan NHRscan GPCRscan PATHscan
Available Available