Targets / Kinase / CAMK2B

calcium/calmodulin-dependent protein kinase II beta (CAMK2B)

Target Class
Kinase
Family
CAMK
Official Symbol
CAMK2B
Entrez Gene ID
816
Species
Human
Accession Number
NP_001211.3
Alias Names
CAM2; CAMK2; CAMKB; CaM kinase II beta subunit; CaM-kinase II beta chain; caMK-II subunit beta; calcium/calmodulin-dependent protein kinase (CaM kinase) II beta; calcium/calmodulin-dependent protein kinase II beta; calcium/calmodulin-dependent protein kinase type II subunit beta; proline rich calmodulin-dependent protein kinase
Background
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Eight transcript variants encoding eight distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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Related Group Members: CAMK
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